DEGRADATION OF MALONIC ACID BY RAT TISSUES
نویسندگان
چکیده
منابع مشابه
Degradation of malonic acid by rat tissues.
In past years, malonate has been extensively used in mammalian systems in vitro as an inhibitor of the citric acid cycle with very little attention given its metabolism per se. Lifson and Stolen (1) demonstrated the conversion of V-labeled malonate to carbon dioxide in the intact mouse. Later, Lee and Lifson (2) found that the administration to rats of doses of U3-labeled malonate at an inhibit...
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Co-crystallizaton of the anti-fungal drug fluconazole [2-(2,4-difluoro-phen-yl)-1,3-bis-(1H-1,2,4-triazol-1-yl)propan-2-ol] with malonic acid in acetonitrile solution resulted in the formation of the title 1:1 co-crystal, C13H12F2N6O·C3H4O4. The geometry around the central fluconazole atom is distorted tetrahedral. The dihedral angles between the triazole rings and the fluorinated phenyl ring a...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1957
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)64814-8